Ying Lu, MD,PhD
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Title
Associate Chief? Doctor, ?Department of Blood Transfusion
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Research Interests
Clinical blood transfusion
Hemapheresis? in hematology disease and immune disease
Autophagy in leukemia
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Education and experiences
Education
Sun Yat-Sen University, Guangzhou, China,?Ph. D?in Hematology ? ? ? ? ? ? ? ? ? ? ? Jun. 2015
Sun Yat-Sen University, Guangzhou China,?Postgraduate?in Hematology ? ? ? ? ?Jun. 2005
Jiangxi Medical College, Jiangxi, China,?MD?in Clinical Medicine ? ? ? ? ? ? ? ? ? ? ? ? Jun. 2002
Experience
Associate Chief? Doctor ?(2017-present)?
????Department of Blood Transfusion, The Third Affiliated Hospital, Sun Yat-Sen University
Attending Physician ?(2015-2016)
????Department of Blood Transfusion, The Third Affiliated Hospital, Sun Yat-Sen University
Attending Physician (2009-2015)
????Department of Hematology, The Third Affiliated Hospital, Sun Yat-Sen University
Resident (2005-2008)
????The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
SELECTED PUBLICATIONS
1 Fan RF,?Lu Y,?Fang ZG,?Guo XY,?Chen YX,?Xu YC,?Lei YM,?Liu KF,?Lin DJ,?Liu LL,?Liu XF. PIM-1?kinase?inhibitor?SMI-4a?exerts?antitumor?effects?in?chronic myeloid leukemia cells by enhancing the activity of glycogen synthase?kinase?3β. Mol Med Rep.?2017, 16: 4603-4612. (Co-first author)
2 Liu X, Fan R, Lu Y, Kuang L, Yuan Q, Chen Y, Lin Z, Lin D.Influence of autologous blood transfusion in liver transplantation in patients with hepatitis B on the function and hemorheology of red blood cells. Exp Ther Med. 2017, 14(2):1205-1211. (Co-first author)
3 Qu C,?Lu Y,?Liu W. Severe bone marrow suppression accompanying pulmonary infection and hemorrhage of the digestive tract associated with leflunomide and low-dose methotrexate combination therapy. J Pharmacol Pharmacother.?2017, 8(1): 35-37.
4 Lu Y, Liu LL, Liu SS, Fang ZG, Zou Y, Deng XB, Long ZJ, Liu Q, Lin DJ. Celecoxib suppresses autophagy and?enhances cytotoxicity of?imatinib in?imatinib- resistant chronic myeloid leukemia cells. J Transl Med.2016, 14: 270
5 Lu Y, Liu XF, Liu TR, Fan RF, Xu YC, Zhang XZ, Liu LL. Celecoxib exerts antitumor effects in HL-60 acute leukemia cells and inhibits autophagy by affecting lysosome function. Biomed Pharmacother. 2016; 84:1551-1557
6 Pan GZ, Zhai FX, Lu Y, Fang ZG, Fan RF, Liu XF, Lin DJ. RUNX3?plays an important role in As2O3?induced apoptosis and allows cells to overcome MSC- mediated drug resistance. Oncol Rep. 2016, 36(4):1927-1938.?
7 Zou Y, Song ZX, Liang XL, Yuan Q,?Liao SH,?Bao JJ. Up-regulation of NKG2A?inhibitory receptor on?circulating?NK?cells?contributes?to?transfusion-induced immune depression in?patients with β- thalassemia?major. J Huazhong Univ Sci Technolog Med Sci.?2016, 36(4):509-513.
8 Fan RF, Chen XY, Fang ZG, Guo XY, Lu Y, Liu LL. Zoledronic?acid overcomes adriamycin resis-
tance?in acute myeloid leukemia cells by promoting apoptosis. Mol Med Rep.?2016, 14(6): 5660-5666.
9 Liu S,?Wang X,?Lu Y,?Xiao J,?Liang J,?Zhong X,?Chen Y. The?combined?use of?cytokine- induced?killer?cells and cyclosporine for the treatment of aplastic anemia in a mouse model. J Interferon Cytokine Res.?2015, 5 (5):401-410
10 Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D. NKP30-B7-H6 interaction?aggrava-
tes?hepatocyte damage through up- regulation of interleukin-32 expression in hepatitis B virus-related acute-on-chronic liver failure. PLoS One.?2015, 10(8): e0134568.
11 Zhai FX,?Liu XF,?Fan RF,?Long ZJ,?Fang ZG,?Lu Y,?Zheng YJ,?Lin DJ. RUNX3?is involved in caspase-3-dependent apoptosis induced by a combination of 5-aza-CdR and TSA in?leukemia?cell lines. J Cancer Res Clin Oncol.?2012, 138(3):439-449.
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Contact
The Third Affiliated Hospital, Sun Yat-sen University
600 Tianhe Road