Wen Xu, MD

Titles

Associate Professor of Endocrinology

The Youth Committee of Endocrinology Association of Guangdong Province

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Research Interests

·Diabetes

·Thyroid disease

·pituitary, adrenal, and gonadal disorders

Besides clinical practice, Professor Wen Xu’s research interests are mainly in performing clinical trials to evaluate the strategies for prevention and management of diabetes. She joined the Diabetes Trials Unit, Oxford University from February, 2010 to January 2011 as a sponsored researcher to undergo further training in conducting large scale randomized clinical trials. She acted as the Clinician Manager, Co-Clinical Lead, and the Chair of Ancillary Study Committee of the ACE Trial which aims to determine whether acarbose therapy can reduce cardiovascular related morbidity and mortality in patients with impaired glucose tolerance and established cardiovascular disease during her stay in DTU. And she is still involved in several multicenter, randomized clinical trials in diabetes conducted in China.

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Education and Experience

Publications (Original articles in English)

1.Wen Xu, Yanhua Zhu, Xubin Yang, Hongrong Deng, Jinhua Yan, Shaoda Lin, Huazhang Yang, Hong Chen, Jianping Weng. Glycemic Variability is an Important Risk Factor for Cardiovascular Autonomic Neuropathy in Newly Diagnosed Type 2 Diabetic Patients. International Journal of Cardiology. 2016; 215: 263-8

2. Wen Xu, Yan Bi, Zilin Sun, Lixin Guo, Tao Yang, Ge Wu, Lixin Shi, hengping Feng, Lin Qiu, Li Qiang, Xiaohui Guo, Zuojie Luo, Juming Lu, Zhongyan Shan, Wenying Yang, Qiuhe Ji, Li Yan, Hong Li, Xuefeng Yu, Shaoqing Li, Zhiguang Zhou, Xiaofeng Lv, Zhen Liang, Shaoda Lin, Longyi Zeng, Jinhua Yan, Li Ji, Jianping Weng. Comparison of Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetes Patients Treated with Exenatide, Insulin or Pioglitazone: a Multicentre Randomized Parallel-group Trial (CONFIDENCE). Journal of Internal Medicine. 2015; 277(1):137-50

3 M Angelyn Bethel, Wen Xu (Co-first), MJ Theodorakis. Pharmacological interventions for preventing or delaying onset of type 2 diabetes mellitus (review). Diabetes, Obesity and Metabolism. 2015; 17(3):231-44

4.Wen Xu, Liling Qiu, Sihui Luo, Ming Li, Jianping Weng, Xiaohui Guo, Linong Ji. Status of Basal-Supported Oral Therapy in Chinese Type 2 Diabetic Patients with Inadequate Glycemic Control on Oral Antidiabetic Drugs. Diabetes/Metabolism Research and Reviews. 2015; 31: 796-802

5. Renyuan Li, Wen Xu (Co-first), Sihui Luo, Haixia Xu, Guoyu Tong, Longyi Zeng, Dalong Zhu, Jianping Weng. Effect of Exenatide, Insulin and Pioglitazone on Bone Metabolism in Patients with Newly Diagnosed Type 2 Diabetes. Acta Diabetol. 2015; 52 (6): 1083-91

6. Bin Yao, Zhaoyi Qin, Ying Tan, Yi He, Jinhua Yan, Qiong Liang, Wen Xu（Co-corresponding author）, Jianping Weng. Rhabdomyolysis in Primary Aldosteronism: A Case Report and Review of the Literature. AACE Clinical Case Rep. 2015; 1:e21-e27

7. Xiaoxu Huo, Leili Gao, Lixin Guo, Wen Xu, Wenbo Wang, Xinyue Zhi, Ling Li, Yanfeng Ren, Xiuying Qi, Zhong Sun, Weidong Li, Qiuhe Ji, Xingwu Ran, Benli Su, Chuanming Hao, Juming Lu, Xiaohui Guo, Hanjing Zhuo, Danyi Zhang, Changyu Pan, Jianping Weng, Dayi Hu, XilinYang, Linong Ji. Risk of non-fatal cardiovascular diseases in early-onset versus late-onset type 2 diabetes in China: a cross-sectional study. The Lancet Diabetes & Endocrinology, 2016; 4 (2):115-24.

8.Wen Xu, Jianping Weng. Current Role of Short Term Intensive Insulin Strategies on Newly Diagnosed Type 2 Diabetes. J Diabetes. 2013; 5(3):268-74.

9.Wen Xu, Yanbing Li, Wanping Deng, Yuantao Hao, Jianping Weng. Remission of hyperglycemia following intensive insulin therapy in newly diagnosed type 2 diabetic patients: a long-term follow-up study. Chin Med J (Engl). 2009; 122(21): 2554-9

10. Jianping Weng, Yanbing Li, Wen Xu, Lixin Shi, Qiao Zhang, Dalong Zhu, Yun Hu, Zhiguang Zhou, Xiang Yan, Haoming Tian, Xingwu Ran, Zuojie Luo, Jing Xian, Li Yan, Fangping Li, Longyi Zeng, Yanming Chen, Liyong Yang, Sunjie Yan, Juan Liu, Ming Li, Zuzhi Fu, Hua Cheng. Effect of intensive insulin therapy on B-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet. 2008; 371: 1753-60

11. Wen Xu, Longyi Zeng, Yanbing Li, Ming Li, Jianping Weng. Intensive insulin therapy in patients with type 2 diabetes-author reply (invited correspondence). Lancet. 2008; 372: 717-8.

12. Li Y, Xu W, Liao Z, Yao B, Chen X, Huang Z, Hu G, Weng JP. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function. Diabetes Care. 2004, 27(11): 2597-2602.

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Contact

Endocrinology department

Third Affiliated Hospital of Sun Yat-sen University

N0. 600, Tianhe Road

Guangzhou, China 510630